Description

Buy Opana online

Oxymorphone is a powerful opioid analgesic used to manage severe pain. It is more potent than morphine (three times), hydrocodone (twice), and oxycodone (twice). This medication is available in immediate-release and extended-release formulations, with effects beginning about 5–10 minutes after injection and 30 minutes after oral administration. Immediate-release tablets provide relief for 3–4 hours, while extended-release tablets last up to 12 hours. The drug is most commonly used orally due to its faster elimination half-life when administered intravenously. Like oxycodone, oxymorphone has a high potential for abuse.

Opana Strengths Available:

• Immediate-Release: 5 mg, 10 mg
• Opana ER (Extended-Release): 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg

Criteria for Use: Opana is prescribed for moderate to severe pain when an opioid is deemed appropriate. It should be used under the supervision of a pain management specialist. The patient must have had intolerable side effects from all other opioid options, which prevented adequate pain control.

Important Warnings:

• Combining Opana with alcohol can increase plasma levels and risk of severe toxicity.
• Take Opana on an empty stomach to avoid a 50% increase in absorption rate caused by food.

Dosage Information:

• For New Users or Those Not Tolerant to Opioids: Start with 5 mg of Opana ER every 12 hours.
• Conversion from Immediate-Release to Extended-Release Oxymorphone: Use the total daily dose of immediate-release oxymorphone, administering half of this dose as extended-release tablets every 12 hours.
• Conversion from Other Oral Opioids: Discontinue all other around-the-clock opioids when starting Opana ER. Use published potency tables or the following conversion factors to estimate the 24-hour oral oxymorphone requirement:
  • Hydrocodone, oxycodone, methadone: Conversion Factor (CF) = 0.5
  • Morphine: CF = 0.333
  • Example: Multiply the total daily dose of the prior opioid by the CF to get the 24-hour oxymorphone dose, then divide by 2 for the starting dose every 12 hours. Adjust as needed.

Side Effects: Seek immediate medical attention for signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Serious side effects may include:

• Slowed or stopped breathing
• Light-headedness or fainting
• Seizures
• Chest pain, wheezing, or cough with discolored mucus
• Severe vomiting
• Symptoms of serotonin syndrome: agitation, hallucinations, fever, sweating, shivering, rapid heart rate, muscle stiffness, nausea, vomiting, diarrhea
• Low cortisol levels: nausea, vomiting, loss of appetite, dizziness, fatigue

Older adults and those who are overweight, malnourished, or debilitated may be at increased risk for severe side effects.

Missed Dose: If a dose is missed, skip it if it’s almost time for your next dose. Do not double up on doses.

Always follow your healthcare provider’s instructions and consult them if you have any questions or concerns about using Opana.